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KMID : 1123920150290010101
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Korean Journal of Oriental Physiology and Pathology
2015 Volume.29 No. 1 p.101 ~ p.113
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Investigation of Anti-microbial Activity of Herbal Medicines Used as Natural Preservatives Based on the Analysis of Papers and Patents
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Kim Jung-Hoon
Do Eui-Jeong
Lee Guem-San
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Abstract
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Application of herbal medicines as natural preservatives has been increased because of its low toxicity or side effect, compared to artificial preservatives. In this study, papers and patents researching anti-microbial activity of herbal medicine were collected and analyzed by the year of publishment, species of bacteria, fungi, or yeasts, and herbal medicines used. After early 2000’s, the number of paper publishment has been decreased, while that of patent registration has been increased up to early 2010’s. Most studied species were Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa , as gram-positive or gram-negative bacteria, and Candida albicans and Aspergillus niger as fungi. The bark of Cinnamomum cassia (L.) J. Presl was most frequently studies herbal medicine, followed by the roots of Scutellaria baicalensis Georgi and Sophora flavescens Ait. This study demonstrates that herbal medicines can be used as natural preservatives against diverse species of bacteria, fungi, or yeasts with their wide-ranged anti-microbial activities.
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KEYWORD
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herbal medicines, natural preservatives, anti-microbial activity, anti-bacterial activity, papers, patents
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